Eur. Phys. J. Plus (2017) 132: 448
https://doi.org/10.1140/epjp/i2017-11703-6

Regular Article

A biomedical solicitation examination of nanoparticles as drug agents to minimize the hemodynamics of a stenotic channel

¹ Department of Mathematics, Faculty of Sciences, HITEC University, 44400, Taxila, Pakistan
² Department of Mathematics, Quaid-i-Azam University 45320, 44000, Islamabad, Pakistan

^* e-mail: shaguftaijaz88@gmail.com

Received: 5 May 2017
Accepted: 12 September 2017
Published online: 2 November 2017

Abstract

A theoretical examination is presented in this analysis to study the flow of a bio-nanofluid through a curved stenotic channel. The curved channel is considered with an overlapping stenotic region. The effect of convective conditions is incorporated to discuss the heat transfer characteristic. The mathematical problem of a curved stenotic channel is formulated and then solved by using the exact technique. To discuss the hemodynamics of a curved stenotic channel the expression of resistance to blood is evaluated by dividing the channel into pre-stenotic, stenotic and post stenotic region. In this investigation gold, silver and copper nanoparticles are used as drug carriers. The outcomes of the graphical illustration reveal that with an increase in nanoparticle concentration hemodynamics effects of stenosed curved channel are reduced and they also conclude that the drug Au nanoparticles are more effective to minimize hemodynamics when compared to the drug Ag and Cu nanoparticles. This analysis finds valuable theoretical information for nanoparticles used as drug agents in the field of bio-inspired applications.