https://doi.org/10.1140/epjp/s13360-024-05099-x
Regular Article
Numerical investigation of novel 2D photonic structure for cancerous cell detection
1
Department of Electronics and Communication Engineering, National Institute of Technology Silchar, 788010, Silchar, Assam, India
2
Indian Institute of Information Technology Bhopal, 462003, Bhopal, India
Received:
29
November
2023
Accepted:
18
March
2024
Published online:
3
April
2024
In this paper, we proposed a novel Swastik photonic sensor (SPS) to detect cancerous cells using human blood samples. The proposed structure has sharp bends at the corner of central rods by introducing line and point defects to achieve better interaction of light with the analytes. The analytes such as Basal, HeLa, Jurkat, PC-12, MDA-MB-231, and MCF-7 are placed individually at the center of the Swastik structure and electric field distribution has been analyzed at ports 1, 2, and 3. We have only obtained a linear relationship between electric field intensity and analytes refractive index at port 2 and calculated all the sensing parameters at the same port using the finite difference time domain (FDTD) method. We have observed the highest sensitivity of 3648.214 nm/RIU at the resonance wavelength of 1566.173 nm for MCF-7 cancerous cells, whereas the highest quality factor (Q) and figure of merit (FoM) is obtained for Jurkat cancerous cell at 1522.189 nm. The highest limit of detection (LoD) and signal-to-noise ratio (SNR) have been achieved at resonance wavelengths of 1505.745 nm and 1524.568 nm, respectively, for Basal and HeLa cancerous cells. We have compared all our calculated values with the available results in the literature.
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© The Author(s), under exclusive licence to Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
