https://doi.org/10.1140/epjp/s13360-024-05022-4
Regular Article
Gold nanoparticles supported on chitosan and the ameliorative response on Raman scattering sensing, catalytic reduction, antibacterial and cytotoxicity activities
1
Department of Botany and Microbiology, College of Science, King Saud University, P.O. 2455, 11451, Riyadh, Saudi Arabia
2
Department of Radiology & Sonar Techniques, Al-Noor University College, Nineveh, Iraq
3
School of Electronic and Information Engineering, Chongqing Three Gorges University, 404000, Chongqing, Wanzhou, China
4
Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq
5
Faculty of Health and Life Sciences, INTI International University, Putra Nilai, 71800, Nilai, Negeri Sembilan, Malaysia
6
Department of Chemistry, Academy of Materials Science, Navi Mumbai, India
a
assyed@ksu.edu.sa
h
bajujanani@gmail.com
Received:
14
October
2023
Accepted:
19
February
2024
Published online:
11
March
2024
In the present study, nanostructures comprising of gold nanoparticles supported on a natural polysaccharide matrix chitosan (Au/CS) were successfully synthesized. The fabricated Au/CS was characterized and investigated for their effectiveness as a surface-enhanced Raman scattering sensing platform for aqueous solutions of malachite green and crystal violet dyes with low detection limits. The Au/CS nanocomposites could serve as a catalyst for efficient degradation of Congo red dye and Cr (VI) metal under reduction process. The removal was found 100% for Congo red dye and Cr (VI) in 25 min and synergy mechanism confirmed by the first-order kinetics study. The antibacterial activity of Au/CS nanocomposites was tested versus Gram+/− pathogenic bacteria. The findings displayed the highest bactericidal progress at a higher concentration. The cytotoxicity of Au/CS nanocomposites was investigated by the breast cancer cell lines. The gold-chitosan nanocomposite has been used for several applications for the first time. The special capability and efficiency of this nanocomposite in these fields are one of the novelties of this study. This work can lead to further manufacturing innovation in the future.
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© The Author(s), under exclusive licence to Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
