https://doi.org/10.1140/epjp/s13360-020-00810-0
Regular Article
The role of diagnosis at early stages to control cervical cancer: a mathematical prediction
1
Department of Mathematics, Jadavpur University, 700032, Kolkata, India
2
Department of Mathematics, Guelma University, 24000, Guelma, Algeria
3
Department of Mathematics, Peter the Great Saint Petersburg Polytechnic University, 195251, Saint Petersburg, Russia
Received:
17
August
2020
Accepted:
25
September
2020
Published online:
6
October
2020
This paper deals with cervical cancer which is the second most common cancer in females and a major cause of death in the world now a days. Detection of symptoms of cervical cancer basically focused at an advance stage. But it is possible to detect cancer at an early stage through diagnosis and screening. The detection through diagnosis at early stages provides the incentive for the primary prevention and helps to slow down the rapid progression of cervical cancer. Considering diagnosis system a time-dependent variable, here we formulate a new mathematical model on cervical cancer considering susceptible human population, cancer patients and diagnosis. This model gives a framework for understanding how early diagnosis increases the chances for cancer patients to be cancer free by providing proper treatment. To explore the in-depth study of the system, we find the basic reproduction number . We analyze and compare the local stability of the equilibrium points of both the systems in the presence and absence of diagnosis. We investigate analytically as well as numerically the causal effect of diagnosis for reducing the cancer patient at an early stage. Furthermore, we enhance the role of diagnosis by using optimal control strategies to prevent the cervical cancer.
Mathematics Subject Classification: 93-XX / 93C15 / 37N35 / 46N10 / 65PXX
Key words: Cervical Cancer / Control Theory / Diagnosis / Treatment
© Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2020