https://doi.org/10.1140/epjp/s13360-024-05935-0
Regular Article
Reactive species emission characteristics of a cold atmospheric pressure plasma source for biomedical applications operated in a test chamber
Faculty of Engineering and Health, HAWK University of Applied Sciences and Arts Hildesheim/Holzminden/Göttingen, Von-Ossietzky-Str. 99, 37085, Göttingen, Lower Saxony, Germany
Received:
9
October
2024
Accepted:
14
December
2024
Published online:
18
January
2025
This study investigates the potentials and limitations of a novel methodology to characterize the reactive species emission dynamics of cold atmospheric plasma sources for biomedical applications. The time-resolved concentrations of ozone and nitrogen oxides during operation of a modified medical device are sampled in a test chamber environment equipped with a stirring fan for effective mixing of species. The interpretation of experimental data is supported by results from a numerical model solving the diffusion-convection equation. From the linear profiles of 
and 
concentrations, emission rates of 1.3−6.4 
for and 
for , depending primarily on plasma input power and fan volume flow rate, were determined for the plasma source. The conversion of these rates into geometry-specific source terms for use in the numerical model led to excellent agreement between experimental and numerical results thus validating the methodology. Finally, empirical equations describing the ozone emission rate dependence on the air flow velocity are presented. The outcomes of this study may stimulate new strategies for assessment of health risks associated with reactive species emission by medical devices based on cold plasma technology.
© The Author(s) 2025
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