https://doi.org/10.1140/epjp/s13360-024-04928-3
Regular Article
Simulation of energy absorption and dose of ionizing radiation on spike of SARS-CoV-2 and comparing it with human mortality statistics, using Geant4-DNA toolkit
1
Department of Physics, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran
2
Department of Microbiology, Parasitology and Immunology, Ardabil University of Medical Sciences, Ardabil, Iran
e chkarami.chiman@gmail.com, c.karami@arums.ac.ir
Received:
19
April
2023
Accepted:
21
January
2024
Published online:
31
January
2024
In this study, variant of concern alpha, gamma and omicron and variant of interest kappa SARS-CoV-2 were simulated by Geant4 tool. Electron, alpha and X-ray beams with different energies hit spike protein, which were located in a box filled with water, and the absorbed energy and dose values were extracted by these proteins. By comparing the amount of energy and absorbed dose spikes with the prevalence rate and statistical analysis of countries affected by the mentioned variants, our study has indicated that there is a reverse relation between absorbed dose and prevalence rate of studied variants. Moreover, the number of protein chains in the spike could play an important role in the amount of energy and absorbed dose. The greater the number of protein chains present in the spike, the less energy and absorbed dose it contains, and the more widespread the variant is likely to be.
Copyright comment Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
© The Author(s), under exclusive licence to Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
