https://doi.org/10.1140/epjp/s13360-023-03672-4
Regular Article
Absorbed dose of 18F-FDG for female patients: Monte Carlo versus MIRD method
Department of Physics, The University of Tabriz, Tabriz, Iran
Received:
12
September
2022
Accepted:
6
January
2023
Published online:
16
January
2023
To estimate the absorbed dose of patients undergoing diagnostic PET with [18F] FDG by using the MIRD and MC methods, a female patient phantom was considered. The organ doses were calculated using the MIRD method and were compared with Monte Carlo calculations. We used the standard organ masses suggested in the ICRP tables for the calculations. The whole body was considered as a source. It was a good agreement between the MIRD and the Monte Carlo calculated doses. The calculated doses especially for metabolically high-uptake tissues such as the bladder, brain, and heart were improved. In this calculation, it was found that urine bladder emptying has a significant impact on the dose of other organs besides the urinary bladder. The MC method calculates doses more accurately than the MIRD method. The calculations showed that the MIRD method calculated doses are 13.02%, 11.19%, and 15.90% lower than MC for EC, gamma annihilation, and gamma decay, respectively. Considering FDG’s particular biokinetics, dosimetry of 18F-FDG based on PET study seems feasible.
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© The Author(s), under exclusive licence to Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
